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Journal of Hepatology
Volume 52, Issue 3, Pages 309-466 (March 2010)

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Editorial Board
page i
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Many Ways One Aim
page ii
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Clinical School Course 14: Metabolic Liver Diseases
page iii
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The International Liver Congress 2010
page iv
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Hepatocellular Carcinoma: from Genomics to Treatment
page v
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Contents
pages vii-viii
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Focus


Focus, 24 December 2009
Daniel Shouval
page 309
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Editorials


Ablation for hepatocellular carcinoma: Is there need to have a winning technique?, 06 January 2010 free full text
Alejandro Forner, Jordi Bruix
pages 310-312
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Harmony in liver fibrosis…, 06 January 2010 free full text
Pierre Bedossa
pages 313-314
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Research Articles

Viral Hepatitis


Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis, 24 December 2009
Mark A.A. Claassen, Robert J. de Knegt, Hugo W. Tilanus, Harry L.A. Janssen, André Boonstra
pages 315-321
Abstract | Full Text | Full-Text PDF (984 KB)


T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer cell suppression in chronic hepatitis B, 06 January 2010
Ying Ju, Nan Hou, Jing Meng, Xiaoyan Wang, Xiaoning Zhang, Di Zhao, Ying Liu, Faliang Zhu, Lining Zhang, Wensheng Sun, Xiaohong Liang, Lifen Gao, Chunhong Ma
pages 322-329
Abstract | Full Text | Full-Text PDF (1026 KB)


A longitudinal analysis of innate and adaptive immune profile during hepatic flares in chronic hepatitis B, 13 January 2010
Anthony T. Tan, Sarene Koh, Winnie Goh, Heng Yee Zhe, Adam J. Gehring, Seng Gee Lim, Antonio Bertoletti
pages 330-339
Abstract | Full Text | Full-Text PDF (1167 KB) | Add-Ons

Cirrhosis


The use of β-adrenergic drugs improves hepatic oxygen metabolism in cirrhotic patients undergoing liver resection, 30 December 2009
Pilar Taurà, Josep Fuster, Jordi Mercadal, Graciela Martinez-Palli, Constantino Fondevila, Annabel Blasi, Jaume Balust, Juan-Carlos Garcia-Valdecasas
pages 340-347
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Encephalopathy assessment in children with extra-hepatic portal vein obstruction with MR, psychometry and critical flicker frequency, 06 January 2010
Santosh K. Yadav, Anshu Srivastava, Arti Srivastava, Michael A. Thomas, Jaya Agarwal, Chandra M. Pandey, Richa Lal, Surender K. Yachha, Vivek A. Saraswat, Rakesh K. Gupta
pages 348-354
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Transplantation


Normal to increased thrombin generation in patients undergoing liver transplantation despite prolonged conventional coagulation tests, 24 December 2009
Ton Lisman, Kamran Bakhtiari, Ilona T.A. Pereboom, Herman G.D. Hendriks, Joost C.M. Meijers, Robert J. Porte
pages 355-361
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Cancer


The αvβ6 integrin is a highly specific immunohistochemical marker for cholangiocarcinoma, 13 January 2010
E. Patsenker, L. Wilkens, V. Banz, C.H. Österreicher, R. Weimann, S. Eisele, A. Keogh, D. Stroka, A. Zimmermann, F. Stickel
pages 362-369
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Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients, 03 August 2009
Valerie Chew, Charlene Tow, Marissa Teo, Hing Lok Wong, Jasmine Chan, Adam Gehring, Marie Loh, Alexandre Bolze, Richard Quek, Victor K.M. Lee, Kang Hoe Lee, Jean-Pierre Abastado, Han Chong Toh, Alessandra Nardin
pages 370-379
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Clinical outcomes of radiofrequency ablation, percutaneous alcohol and acetic acid injection for hepatocelullar carcinoma: A meta-analysis, 18 January 2010
Giacomo Germani, Maria Pleguezuelo, Kurinchi Gurusamy, Tim Meyer, Graziella Isgrò, Andrew Kenneth Burroughs
pages 380-388
Abstract | Full Text | Full-Text PDF (964 KB)

Molecular and Cell Biology


Advanced glycation end products induce production of reactive oxygen species via the activation of NADPH oxidase in murine hepatic stellate cells, 24 December 2009
Eduardo L.M. Guimarães, Christophe Empsen, Albert Geerts, Leo A. van Grunsven
pages 389-397
Abstract | Full Text | Full-Text PDF (1228 KB)


Fibrillar collagen scoring by second harmonic microscopy: A new tool in the assessment of liver fibrosis, 18 January 2010
Luc Gailhouste, Yann Le Grand, Christophe Odin, Dominique Guyader, Bruno Turlin, Frédéric Ezan, Yoann Désille, Thomas Guilbert, Anne Bessard, Christophe Frémin, Nathalie Theret, Georges Baffet
pages 398-406
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TGF-β enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I, 06 January 2010
Loredana Ciuclan, Sabrina Ehnert, Iryna Ilkavets, Hong-Lei Weng, Haristi Gaitantzi, Hidekazu Tsukamoto, Elke Ueberham, Nadja M. Meindl-Beinker, Manfred V. Singer, Katja Breitkopf, Steven Dooley
pages 407-416
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Genetic and Metabolic Diseases


Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria, 23 September 2009
Carmen Unzu, Ana Sampedro, Itsaso Mauleón, Lucía Vanrell, Juan Dubrot, Rafael Enríquez de Salamanca, Gloria González-Aseguinolaza, Ignacio Melero, Jesús Prieto, Antonio Fontanellas
pages 417-424
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Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis, 06 January 2010
Anita C.G. Chua, Roheeth D. Delima, Evan H. Morgan, Carly E. Herbison, Janina E.E. Tirnitz-Parker, Ross M. Graham, Robert E. Fleming, Robert S. Britton, Bruce R. Bacon, John K. Olynyk, Debbie Trinder
pages 425-431
Abstract | Full Text | Full-Text PDF (1972 KB)

Reviews


Congenital disorders of glycosylation in hepatology: The example of polycystic liver disease, 24 December 2009
Manoe J. Janssen, Esmé Waanders, Jannes Woudenberg, Dirk J. Lefeber, Joost P.H. Drenth
pages 432-440
Abstract | Full Text | Full-Text PDF (992 KB)


Is response to antiviral treatment influenced by hepatitis B virus genotype?, 06 January 2010
Sara Raimondi, Patrick Maisonneuve, Savino Bruno, Mario U. Mondelli
pages 441-449
Abstract | Full Text | Full-Text PDF (508 KB)

Special Sections

International Hepatology


International Hepatology, 06 January 2010
Shannon S. Glaser, Gianfranco Alpini
pages 450-451
Abstract | Full Text | Full-Text PDF (197 KB)


Genetic polymorphism and response to treatment in chronic hepatitis C: The future of personalized medicine, 07 January 2010
Tarik Asselah
pages 452-454
Abstract | Full Text | Full-Text PDF (457 KB)

Meeting Report


The new therapeutic frontier – Nuclear receptors and the liver, 24 December 2009
Saul J. Karpen, Michael Trauner
pages 455-462
Abstract | Full Text | Full-Text PDF (719 KB) | Add-Ons

Letter to the Editor


Reactivation of hepatitis B virus after transarterial chemo-embolization for hepatocellular carcinoma in one patient with negative hepatitis B surface antigen, 24 December 2009
Hung-Hsu Hung, Chien-Wei Su, Jaw-Ching Wu, Shou-Dong Lee
pages 463-465
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Corrigendum


Corrigendum to “Acute hepatitis caused by a natural lipid-lowering product: When “alternative” medicine is no “alternative” at all” [J Hepatol 50 (2009) 1273–1277], 06 January 2010 free full text
Antonio Grieco, Luca Miele, Maurizio Pompili, Marco Biolato, Fabio M. Vecchio, Ignazio Grattagliano, Giovanni Gasbarrini
page 466
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