Journal of Hepatology
Volume 50, Issue 6 , Pages 1236-1246, June 2009

Polyenephosphatidylcholine prevents alcoholic liver disease in PPARα-null mice through attenuation of increases in oxidative stress☆

  • Wataru Okiyama

      Affiliations

    • Department of Metabolic Regulation, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan
    • Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan
    • These authors contributed equally to this work.
    • ,
  • Naoki Tanaka

      Affiliations

    • Department of Metabolic Regulation, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan
    • Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan
    • Corresponding Author InformationCorresponding author. Fax: +81 263 37 3094.
    • These authors contributed equally to this work.
    • ,
  • Tamie Nakajima

      Affiliations

    • Department of Occupational Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan
    • ,
  • Eiji Tanaka

      Affiliations

    • Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan
    • ,
  • Kendo Kiyosawa

      Affiliations

    • Department of Internal Medicine, Nagano Red Cross Hospital, Nagano, Japan
    • ,
  • Frank J. Gonzalez

      Affiliations

    • Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    • ,
  • Toshifumi Aoyama

      Affiliations

    • Department of Metabolic Regulation, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan

Received 8 December 2008; received in revised form 18 January 2009; accepted 27 January 2009. published online 02 April 2009.

Associate Editor: C.P. Day

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☆ The authors who have taken part in this study declared that they do not have anything to disclose regarding funding or conflict of interest with respect to this manuscript.

PII: S0168-8278(09)00155-X

doi:10.1016/j.jhep.2009.01.025

Journal of Hepatology
Volume 50, Issue 6 , Pages 1236-1246, June 2009

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