Journal of Hepatology
Volume 48, Issue 5 , Pages 728-735, May 2008

Lamivudine compared with lamivudine and adefovir dipivoxil for the treatment of HBeAg-positive chronic hepatitis B☆

  • Joseph J.Y. Sung

      Affiliations

    • Department of Medicine and therapeutics, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, People’s Republic of China
    • Corresponding Author InformationCorresponding author. Tel.: +852 2632 3127; fax: +852 2645 1699.
    • ,
  • Jak-Yiu Lai

      Affiliations

    • Department of Medicine, Princess Margaret Hospital, Lai Chi Kok, Hong Kong, China
    • ,
  • Stefan Zeuzem

      Affiliations

    • Department of Internal Medicine II, University Hospital, Homburg/Saar, Germany
    • ,
  • Wan Chen Chow

      Affiliations

    • Gastroenterology Department, Singapore General Hospital, Singapore
    • ,
  • E. Jenny Heathcote

      Affiliations

    • University Health Network, Toronto Western Hospital, University of Toronto, Canada
    • ,
  • Robert P. Perrillo

      Affiliations

    • Department of Gastroenterology, Ochsner Clinic, New Orleans, LA, UK
    • ,
  • Carol L. Brosgart

      Affiliations

    • Gilead Sciences, Foster City, CA, UK
    • ,
  • Mary A. Woessner

      Affiliations

    • GlaxoSmithKline Research and Development, Research Triangle Park, NC, UK
    • ,
  • Susan A. Scott

      Affiliations

    • GlaxoSmithKline Research and Development, Greenford, Middlesex, UK
    • ,
  • D. Fraser Gray

      Affiliations

    • GlaxoSmithKline Research and Development, Greenford, Middlesex, UK
    • ,
  • Stephen D. Gardner

      Affiliations

    • GlaxoSmithKline Research and Development, Research Triangle Park, NC, UK

Received 29 July 2007; received in revised form 10 December 2007; accepted 11 December 2007. published online 28 February 2008.

Associate Editor: F. Zoulim

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☆ Clinical trial registration: NUC20912; GlaxoSmithKline Clinical Trial Register; http://ctr.gsk.co.uk. Dr. Brosgart is employee of Gilead Sciences, Foster City, CA. Drs. Woessner and Gardner are employees of GlaxoSmithKline Research and Development, Research Triangle Park, NC. Drs. Gray and Scott are employees of GlaxoSmithKline Research and Development, Greenford, Middlesex, UK. The other authors who have taken part in the research of this paper declared that they do not have a relationship with the manufacturers of the drug involved either in the past or present. They received funding from the manufacturers to carry out their research with the exception of Drs. Lai and Perrillo.

PII: S0168-8278(08)00121-9

doi:10.1016/j.jhep.2007.12.026

Journal of Hepatology
Volume 48, Issue 5 , Pages 728-735, May 2008

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